Introduction
 
This standard is revised on the basis of the original standard of Q/PSH001-2010 "3.5% Polyoxin AS".
The main differences between this standard and that of Q/PSH001-2010 are:
The mass fraction of polyoxin in this standard is revised from "3.5 ± 0.4" to "5 ± 0.5"
 
Other name, structural formula and basic physical and chemical parameters of active ingredients of the product are as follows:
Common name in ISO：Polyoxin
Chemical name: antibiotics of peptide pyrimidine nucleic acid, the main components are: 5 - {[2 - amino -5-0 - (carbamoyl)-2 –deoxy-L-xylose] amino} -1, 5 – di-deoxy-1 - [1,2,3,4 – tetrahydro-5 - (hydroxyl-methyl) -2,4 - dioxopyr-(2H) - pyrimidinyl]-D Be-furan uronic acid
The structural formula is:
                          
Empirical formula: C₁₇H₂₅N₅O₁₃
Relative molecular weight: 507.40600
 

Inspection Item	Specifications	Measured Result
Mass fraction of Polyoxin	5±0.5	5.2
Range of pH value	3.0 – 6.0	4.7
Water insoluble matter	≤0.3	0.1
Dilution stability	Qualified	Qualified
Stability at low temperature	Qualified	Qualified
Mass fraction of Polyoxin after heat storage, %	≥4.9	5.1
Dilution stability after heat storage	Qualified	Qualified

 
 
polyoxin B
IUPA Cname 5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido)-1,5-dideoxy-1-(1,2,3,4-tetrahydro-5-hydroxymethyl-2,4-dioxopyrimidin-1-yl)-b-D-allofuranuronic acid， Chemical Abstracts name 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-b-D-allofuranuronic acid , CAS RN [19396-06-6]  
Mol. wt. 507.4  M.f. C17H25N5O13  Form Amorphous powder.  M.p. >188 篊 (decomp.)  V.p. <1.33 ?105 mPa (20, 30 and 40 癈)  KOW logP = -1.21  S.g./density 0.536 (23 癈)  Solubility In water >1 kg/l (20 篊). In acetone 13.5, methanol 2250, toluene, dichloromethane and ethyl acetate <0.65 (all in mg/l, 20 篊).  Stability Hygroscopic, and thus should be stored in tightly closed containers under dry conditions. Stable between pH 1 and pH 8.  Specific rotation [a]D20 +34?(c = 1, water)  pKa pKa1 (carboxyl) 2.65, pKa2 (amino) 7.25, pKa3 (uracil) 9.52
 
olyoxin B
Uses Polyoxin B is used for control of Alternaria spp. and powdery mildews in apples and pears; Botrytis cinerea in vines and aubergines; powdery mildews in roses, chrysanthemums, capsicums, and melons; blight of carnations; powdery mildew, brown spot, and grey mould in tobacco; powdery mildew and grey mould in strawberries; leaf mould, early blight, and grey mould in tomatoes; powdery mildew, grey mould, Sclerotinia rot, and Corynespora in cucumbers; Alternaria blight in carrots; purple blotch in leeks; etc. Formulation types EC; SG; WP.  Compatibility Incompatible with alkaline materials.  Selected products: 'Polyoxin AL' (Kaken, Kumiai, Nihon Nohyaku, Hokko)